In vivo antitussive activity of Coccinia grandis against irritant aerosol and sulfur dioxide-induced cough model in rodents
نویسنده
چکیده
Bangladesh J Pharmacol 2009; 4: 84-87 Journal homepage: www.banglajol.info; www.bdjpharmacol.com Abstracted/indexed in Academic Search Complete, Agroforestry Abstracts, Asia Journals Online, Bangladesh Journals Online, Biological Abstracts, BIOSIS Previews, CAB Abstracts, Current Abstracts, Directory of Open Access Journals, EMBASE/Excerpta Medica, Google Scholar, HINARI (WHO), International Pharmaceutical Abstracts, Open J-gate, Science Citation Index Expanded and Social Sciences Citation Index ISSN: 1991-007X (Print); 1991-0088 (Online); DOI: 10.3329/bjp.v4i2.1537
منابع مشابه
Antitussive activity of ethanolic extract of Curcuma aromatica rhizomes on sulfur dioxide induced cough in mice
Ethanolic extract of rhizomes of Curcuma aromatica (Zingiberaceae) was investigated for its antitussive effect on Sulfur dioxide induced cough model in mice. The extract exhibited significant antitussive activity in a dose dependant manner. The activity was compared with the prototype antitussive agent codeine phosphate. The ethanolic extract at the dose of lOOmg. 200mg and 400mg/kg body weight...
متن کاملAntibacterial, antioxidant and cell proliferative properties of Coccinia grandis fruits
Objective: Little knowledge is available on the antimicrobial and antioxidant properties of Coccina grandis fruits and no study has reported on its cell proliferative property. The aim of this study was to examine the antimicrobial, antioxidant and cell proliferative property of fruits of C. grandis. Material and Methods: Fruits of C. grandis were extracted using water; ethanol and acetone by c...
متن کاملEvaluation of antitussive activity of formulations with herbal extracts in sulphur dioxide (SO2) induced cough model in mice.
Cough is the most common symptom of respiratory diseases. When cough becomes serious, opioids are effective, but they have side effects like sedation, constipation, some addiction liability and also compromise the respiratory function. Therefore, there is need to have effective anti-tussive agent which do not have respiratory suppressant activity. The present study was carried out to evaluate a...
متن کاملAntitussive activity of sigma-1 receptor agonists in the guinea-pig.
1. Current antitussive medications have limited efficacy and often contain the opiate-like agent dextromethorphan (DEX). The mechanism whereby DEX inhibits cough is ill defined. DEX displays affinity at both NMDA and sigma receptors, suggesting that the antitussive activity may involve central or peripheral activity at either of these receptors. This study examined and compared the antitussive ...
متن کاملAntitussive effect of Portulaca oleracea L. in guinea pigs
Several therapeutic effects including diuretic, anti-pyretic and anti-scurvy have been reported for Portulaca oleracea. In previous studies the analgesic, anti-inflammatory, anti-hypertensive, anti-oxidant, muscle relaxant effects and neuropharmacological effects of the aqueous extract of Portulaca oleracea have been demonstrated on experimental animals. In the present study the antitussive eff...
متن کامل